"Rabinovich discovered galectin-1, which he described as the sweet case of Dr. Jekyll and Mr. Hyde, highlighting its dual role in the immune system."
"The immune system needs to maintain a delicate balance, and in certain pathological situations, it can go one way or the other, requiring fine-tuning."
"Three decades after his initial experiments, Rabinovich is still working with galectin-1, preparing experiments to modulate this molecular switch in diseases."
Gabriel Rabinovich's career began unexpectedly in a chicken retina lab, where he discovered galectin-1, a protein with dual roles in the immune system. Galectin-1 helps restore immune balance after threats but can also aid tumors in evading immune responses. This discovery revolutionized understanding of immune regulation and opened avenues for new therapies targeting autoimmune diseases and cancer. Rabinovich continues to research galectin-1, focusing on its modulation in conditions like multiple sclerosis and cancer, emphasizing the need for immune system balance.
Read at english.elpais.com
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