The 2025 Africa Cup of Nations (Afcon) will significantly impact the Premier League, with 49 players potentially unavailable during its duration from December 21, 2025, to January 18, 2026. Key stars like Mohamed Salah and Bryan Mbuemo could miss up to eight matches, including six league fixtures and important cup matches. Currently, 54 players from African nations play in the Premier League, but some, like Mohammed Kudus and Antoine Semenyo, will not participate due to their countries not qualifying. Clubs face considerable selection challenges during this period.
A total of 49 Premier League players could miss part of the season due to the 2025 Africa Cup of Nations (Afcon), highlighting significant scheduling challenges.
The next edition of Afcon will take place in Morocco from December 21, 2025, to January 18, 2026, resulting in clubs losing key players during winter fixtures.
Several key players, including Liverpool's Mohamed Salah and Manchester United's Bryan Mbuemo, may be called up for Afcon, intensifying concerns for struggling clubs.
Between December 21, 2025, and January 18, 2026, a total of six Premier League match rounds are scheduled, as well as critical cup fixtures.
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