#genetic-architecture

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#ancient-dna #directional-selection #human-evolution #complex-traits #autism-spectrum-disorder
Data science
fromNature
3 weeks ago

Ancient DNA reveals pervasive directional selection across West Eurasia - Nature

Ancient DNA analysis reveals strong directional selection affecting hundreds of alleles in the last ten millennia, influencing complex traits in modern populations.
Science
fromNature
3 months ago

Developmental convergence and divergence in human stem cell models of autism - Nature

Distinct rare mutations and common genetic variation jointly shape ASD risk, yet convergent molecular pathology and early fetal neurodevelopmental mechanisms can be studied using stem-cell models.
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