#lineage-tracing

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Cancer
fromNature
6 months ago

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature

Fluctuating CpG methylation enables EVOFLUx to reconstruct quantitative cancer evolutionary histories from clinical bulk samples at scale, informing dynamics and clinical outcomes.
SF politics
fromNature
10 months ago

Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature

Lineage tracing requires methods that utilize endogenous clonal markers for broader applications, especially in human studies and aging.
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