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fromNews Center
3 days ago

Study Identifies Gene Linked to Rare Ciliopathy Disorders - News Center

Ciliopathies, a group of genetic disorders, are caused by defects in the structure or function of cilia, tiny hair-like organelles found on nearly all cells in the body. These cilia act as sensory and signaling hubs, playing critical roles in development, tissue maintenance and physiological processes. When they malfunction, they disrupt cellular signaling and transport, leading to widespread effects across multiple organ systems.
Science
Medicine
fromNature
1 month ago

Proteotoxic stress response drives T cell exhaustion and immune evasion - Nature

Proteomic profiling of exhausted T cells reveals pathway-specific transcript–protein discordance and identifies T cell–exhaustion-specific protein-level regulatory mechanisms.
Medicine
fromNature
1 month ago

SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer - Nature

SPP1 plasma levels increase in late-stage pancreatic ductal adenocarcinoma and in KPCY mouse models, correlating with mesenchymal marker analyses and organoid-based tumor assays.
Science
fromNature
3 months ago

One potent gene raises risk of Alzheimer's, Parkinson's and other brain diseases

APOE ε4 increases vulnerability to various neurodegenerative diseases, including Alzheimer's, Parkinson's, and motor neuron diseases.
OMG science
fromBusiness Insider
4 months ago

Forget 'biological age' tests - longevity experts are using an $800 under-the-radar blood test to measure aging in real-time

A forthcoming blood test could help tailor health decisions based on unique biology.
The organ age test (proteomics) may be a better biological age marker for assessing health.
fromNews Center
6 months ago

Novel Approach Improves Protein Characterization in Human Tissue - News Center

This technology can give you a global picture of the proteins included in one specific cell or tissue region as small as possible that can be laser captured and microdissected. This technology can be broadly applied to analyzing any cell in any tissue in a spatially-preserved manner.
OMG science
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